Article
Clinical features and treatment outcome of non-small cell lung cancer (NSCLC) patients with uncommon or complex epidermal growth factor receptor (EGFR) mutations.
Oncotarget - 16 May 2017
Frega Stefano, Lorenzi Martina, Fassan Matteo, Indraccolo Stefano, Calabrese Fiorella, Favaretto Adolfo, Bonanno Laura, Polo Valentina, Zago Giulia, Lunardi Francesca, Attili Ilaria, Pavan Alberto, Rugge Massimo, Guarneri Valentina, Conte PierFranco, Pasello Giulia
Abstract excerpt
INTRODUCTION: Tyrosine-kinase inhibitors (TKIs) represent the best treatment for advanced non-small cell lung cancer (NSCLC) with common exon 19 deletion or exon 21 epidermal growth factor receptor mutation (EGFRm). This is an observational study investigating epidemiology, clinical features and treatment outcome of NSCLC cases harbouring rare/complex EGFRm. RESULTS: Among 764 non-squamous NSCLC cases with known...
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