Article
Detection of Polish clinical Aspergillus fumigatus isolates resistant to triazoles.
Medical mycology - 1 Jan 2018
Nawrot Urszula, Kurzyk Ewelina, Arendrup Maiken Cavling, Mroczynska Martyna, Wlodarczyk Katarzyna, Sulik-Tyszka Beata, Wróblewska Marta, Ussowicz Marek, Zdziarski Przemyslaw, Niewinska Kinga, Brillowska-Dabrowska Anna
Abstract excerpt
We studied the presence of triazole resistance of 121 Aspergillus fumigatus clinical isolates collected in two Polish cities, Warsaw and Wrocław, to determine if resistance is emerging in our country. We identified five itraconazole resistant isolates (4.13%) carrying the TR34/L98H alteration in Cyp51A gene, four of which were cross-resistant to posaconazole and one to voriconazole. One isolate was intermediate...
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