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Article

Intergenerational response to the endocrine disruptor vinclozolin is influenced by maternal genotype and crossing scheme.

Reproductive toxicology (Elmsford, N.Y.) - 1 Jun 2018

Pietryk Edward W, Clement Kiristin, Elnagheeb Marwa, Kuster Ryan, Kilpatrick Kayla, Love Michael I, Ideraabdullah Folami Y

Abstract excerpt

In utero exposure to vinclozolin (VIN), an antiandrogenic fungicide, is linked to multigenerational phenotypic and epigenetic effects. Mechanisms remain unclear. We assessed the role of antiandrogenic activity and DNA sequence context by comparing effects of VIN vs. M2 (metabolite with greater antiandrogenic activity) and wild-type C57BL/6 (B6) mice vs. mice carrying mutations at the previously reported...

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Identifiers

PMID: 29535025
DOI: 10.1016/j.reprotox.2018.03.005
PMCID: PMC5984144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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