Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phosphoproteomics Enables Molecular Subtyping and Nomination of Kinase Candidates for Individual Patients of Diffuse-Type Gastric Cancer

6 Nov 2019

Abstract excerpt

The diffuse-type gastric cancer (DGC) constitutes a subgroup of gastric cancer with poor prognosis and no effective molecular therapies. Here, we report a phosphoproteomic landscape of DGC derived from 83 tumors together with their nearby tissues. Based on phosphorylation, DGC could be classified into three molecular subtypes with distinct overall survival (OS) and chemosensitivity. We identified 16 kinases whose...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Colorectal Cancer Treatments and Studies
Share to Gastric Cancer Management and Outcomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31751824
DOI: 10.1016/j.isci.2019.11.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phosphoproteomics Enables Molecular Subtyping and Nomination of Kinase Candidates for Individual Patients of Diffuse-Type Gastric CancerPMID 31751824Read ↗

A proteomic landscape of diffuse-type gastric cancer.Semantic proximity Read ↗

Comprehensive pharmacogenomic characterization of gastric cancer.Semantic proximity Read ↗

Molecular Profiling of Gastric Cancer: Toward Personalized Cancer MedicineSemantic proximity Read ↗

Multilevel proteomic analyses reveal molecular diversity between diffuse-type and intestinal-type gastric cancer.Semantic proximity Read ↗

Signaling pathways and therapeutic interventions in gastric cancerSemantic proximity Read ↗

Identification of a molecular signature of prognostic subtypes in diffuse-type gastric cancerSemantic proximity Read ↗

Integrative kinomics reveals kinase-driven subtypes of gastric adenocarcinomas with sunitinib as a potential common inhibitorSemantic proximity Read ↗

Phosphoproteomic subtyping of gastric cancer reveals dynamic transformation with chemotherapy and guides targeted cancer treatmentSemantic proximity Read ↗

Evolving Molecular Subtypes of Gastric Cancer: From Past Classifications to Present Consensus and Future Directions for Precision TherapySemantic proximity Read ↗

Dynamic phospho-proteogenomic analysis of gastric cancer cells suggests host immunity provides survival benefitSemantic proximity Read ↗

The metabolic subtypes of gastric cancer reveal treatment preferencesSemantic proximity Read ↗

AURKB is a key to connect oxidative phosphorylation and immune microenvironment in Gastric Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.