Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

23S rRNA and L22 ribosomal protein are involved in the acquisition of macrolide and lincosamide resistance in Mycoplasma capricolum subsp. capricolum.

Veterinary microbiology - 1 Mar 2018

Prats-van der Ham Miranda, Tatay-Dualde Juan, Gómez-Martín Ángel, Corrales Juan Carlos, Contreras Antonio, Sánchez Antonio, de la Fe Christian

Abstract excerpt

Mycoplasma capricolum subsp. capricolum (Mcc) is one of the causative agents of contagious agalactia, and antimicrobial therapy is the most commonly applied measure to treat outbreaks of this disease. Macrolides and lincosamides bind specifically to nucleotides at domains II and V of the 23S rRNA. Furthermore, rplD and rplV genes encode ribosomal proteins L4 and L22, which are also implicated in the macrolide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lincosamides

Share to Macrolides

Share to Microbial Sensitivity Tests

Share to Point Mutation

Share to Ribosomal Proteins

Share to RNA, Ribosomal, 23S

Source

Identifiers

PMID: 29519518
DOI: 10.1016/j.vetmic.2018.02.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

23S rRNA and L22 ribosomal protein are involved in the acquisition of macrolide and lincosamide resistance in Mycoplasma capricolum subsp. capricolum.PMID 29519518Read ↗

Antimicrobial susceptibility and multilocus sequence typing of Mycoplasma capricolum subsp. capricolum.Semantic proximity Read ↗

Resistance mechanisms against quinolones in Mycoplasma capricolum subsp. capricolum.Semantic proximity Read ↗

Genetic diversity and evolution of Mycoplasma capricolum subsp. capripneumoniae strains from eastern Africa assessed by 16S rDNA sequence analysis.Semantic proximity Read ↗

Multilocus sequence typing of Mycoplasma mycoides subsp. capri to assess its genetic variability in a contagious agalactia endemic area.Semantic proximity Read ↗

Mutations in the quinolone resistance determining region conferring resistance to fluoroquinolones in Mycoplasma agalactiae.Semantic proximity Read ↗

Ribosomal Mutations Conferring Macrolide Resistance in Legionella pneumophila.Semantic proximity Read ↗

Phylogeny of the Mycoplasma mycoides cluster as determined by sequence analysis of the 16S rRNA genes from the two rRNA operonsSemantic proximity Read ↗

Genomic variations of Mycoplasma capricolum subsp. capripneumoniae detected by amplified fragment length polymorphism (AFLP) analysis.Semantic proximity Read ↗

Mycoplasma bovis isolates from dairy calves in Japan have less susceptibility than a reference strain to all approved macrolides associated with a point mutation (G748A) combined with multiple species-specific nucleotide alterations in 23S rRNA.Semantic proximity Read ↗

Transition mutations in 23S rRNA account for acquired resistance to macrolides in Ureaplasma urealyticum.Semantic proximity Read ↗

23S rRNA 2058A-->G alteration mediates ketolide resistance in combination with deletion in L22.Semantic proximity Read ↗

Mechanisms involved in quinolone resistance in Mycoplasma mycoides subsp. capri.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.