Article
Transition mutations in 23S rRNA account for acquired resistance to macrolides in Ureaplasma urealyticum.
Microbial drug resistance (Larchmont, N.Y.) - 1 Sept 2008
Dongya Meng, Wencheng Xue, Xiaobo Ma, Lu Wang
Abstract excerpt
OBJECTIVE: To study the mechanisms of acquired resistance of Ureaplasma urealyticum (Uu) to Macrolide antibiotics. METHODS: Eighteen strains of Uu clinical isolates with different phenotypes of resistance to Macrolide antibiotics were screened for mutations in 23S rRNA in comparison with the reference strain ATCC 27618 and AF272627-1 in GenBank, which is susceptible to Macrolide antibiotics. RESULTS: Compared to...
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