Article
Resistance mechanisms against quinolones in Mycoplasma capricolum subsp. capricolum.
Veterinary journal (London, England : 1997) - 1 May 2017
Tatay-Dualde Juan, Prats-van der Ham Miranda, de la Fe Christian, Paterna Ana, Sánchez Antonio, Corrales Juan Carlos, Contreras Antonio, Gómez-Martin Ángel
Abstract excerpt
Quinolones interact with bacterial DNA gyrase and topoisomerase IV, the subunits of which are encoded by gyrA/gyrB and parC/parE, respectively. The aim of this study was to evaluate the relationship between changes in these genes and quinolone susceptibility of Mycoplasma capricolum subsp. capricolum (Mcc). Using in vitro selected resistant mutants and field isolates from goats, predicted amino acid changes in...
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