Article
Egg-specific IgE and basophil activation but not egg-specific T-cell counts correlate with phenotypes of clinical egg allergy.
The Journal of allergy and clinical immunology - 1 Jul 2018
Berin M Cecilia, Grishin Alexander, Masilamani Madhan, Leung Donald Y M, Sicherer Scott H, Jones Stacie M, Burks A Wesley, Henning Alice K, Dawson Peter, Grabowska Joanna, Agashe Charuta, Davidson Wendy F, Wood Robert A, Sampson Hugh A
Abstract excerpt
BACKGROUND: Egg allergy is phenotypically heterogeneous. A subset of patients with egg allergy can tolerate egg in an extensively heated form. Inclusion of baked egg (BE) into the diet accelerates resolution of egg allergy. Conversely, BE reactivity is associated with persistent disease. The immune basis of this clinical heterogeneity is unknown. OBJECTIVES: We sought to study egg-specific antibody, basophil, and...
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