Article
Transcriptional Profiling of Egg Allergy and Relationship to Disease Phenotype.
PloS one - 1 Jan 2016
Kosoy Roman, Agashe Charuta, Grishin Alexander, Leung Donald Y, Wood Robert A, Sicherer Scott H, Jones Stacie M, Burks A Wesley, Davidson Wendy F, Lindblad Robert W, Dawson Peter, Merad Miriam, Kidd Brian A, Dudley Joel T, Sampson Hugh A, Berin M Cecilia
Abstract excerpt
BACKGROUND: Egg allergy is one of the most common food allergies of childhood. There is a lack of information on the immunologic basis of egg allergy beyond the role of IgE. OBJECTIVE: To use transcriptional profiling as a novel approach to uncover immunologic processes associated with different phenotypes of egg allergy. METHODS: Peripheral blood mononuclear cells (PBMCs) were obtained from egg-allergic children...
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