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Article

Differential T follicular helper cell phenotypes distinguish IgE-mediated milk allergy from eosinophilic esophagitis in children.

The Journal of allergy and clinical immunology - 1 Mar 2025

Lozano-Ojalvo Daniel, Chen Xin, Kazmi Wajiha, Menchén-Martínez David, Pérez-Rodríguez Leticia, Fernandes-Braga Weslley, Tyler Scott, Benkov Keith, Pittman Nanci, Lai Joanne, Sampson Hugh A, Curotto de Lafaille Maria, Dunkin David, Berin M Cecilia

Abstract excerpt

BACKGROUND: IgE-mediated food allergy and eosinophilic esophagitis (EoE) are diseases commonly triggered by milk. Milk-responsive CD4+ T cells producing type 2 cytokines are present in both diseases, yet the clinical manifestation of disease in milk allergy (MA) and EoE are distinct. OBJECTIVE: We sought to identify differences in CD4+ T cells between EoE and MA that may be responsible for distinct disease...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39389123
DOI: 10.1016/j.jaci.2024.09.024
PMCID: PMC11895100

Genes

CD4
CD38

Provenance

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