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Article

DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia

5 Mar 2018

Abstract excerpt

Few biological markers are associated with survival after relapse of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). In pediatric T-cell ALL, we have identified promoter-associated methylation alterations that correlate with prognosis. Here, the prognostic relevance of CpG island methylation phenotype (CIMP) classification was investigated in pediatric BCP-ALL patients. Six hundred and one BCP-ALL...

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PMID: 29515676
DOI: 10.1186/s13148-018-0466-3

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