Article
Evaluating the relationship between alcohol consumption, tobacco use, and cardiovascular disease: A multivariable Mendelian randomization study.
PLoS medicine - 1 Dec 2020
Rosoff Daniel B, Davey Smith George, Mehta Nehal, Clarke Toni-Kim, Lohoff Falk W
Abstract excerpt
BACKGROUND: Alcohol consumption and smoking, 2 major risk factors for cardiovascular disease (CVD), often occur together. The objective of this study is to use a wide range of CVD risk factors and outcomes to evaluate potential total and direct causal roles of alcohol and tobacco use on CVD risk factors and events. METHODS AND FINDINGS: Using large publicly available genome-wide association studies (GWASs)...
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