Article
Abundant expression of the membrane-anchored protease-regulator RECK in the anterior pituitary gland and its implication in the growth hormone/insulin-like growth factor 1 axis in mice.
Molecular and cellular endocrinology - 15 May 2020
Ogawa Shuichiro, Matsuzaki Tomoko, Noda Makoto
Abstract excerpt
The tumor suppressor gene Reversion-inducing cysteine-rich protein with Kazal motifs (Reck) encodes a membrane-anchored protease regulator expressed in multiple tissues in mouse embryos and is essential for embryonic development. In postnatal mice, however, physiological roles for the RECK protein remain unclear. We found in this study that Reck is abundantly expressed in growth hormone (GH)-producing cells...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.