Epigenetic regulation of placental gene expression in transcriptional subtypes of preeclampsia

Abstract excerpt

Background: = 330), of which four (clusters 1, 2, 3, and 5) contained a substantial number of PE samples. However, while transcriptional analysis of placentas can subtype patients, we propose that the addition of epigenetic information could discern gene regulatory mechanisms behind the distinct PE pathologies, as well as identify clinically useful potential biomarkers. Results: We subjected 48 of our samples...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Neonatal and fetal brain pathology
• Share to Pregnancy and preeclampsia studies
• Share to Prenatal Screening and Diagnostics