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Epigenome-wide DNA methylation profiling of preeclamptic placenta according to severe features

24 Aug 2020

Abstract excerpt

BACKGROUND: Preeclampsia (PE) is an obstetric disorder with significant morbidities for both the mother and fetus possibly caused by a failure of the placental trophoblast invasion. However, its pathophysiology largely remains unclear. Here, we performed DNA methylation profiling to determine whether differential patterns of DNA methylation correlate with PE and severe features of PE. MATERIALS AND METHODS: We...

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PMID: 32831145
DOI: 10.1186/s13148-020-00918-1

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