Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative proteomic and phosphoproteomic comparison of human colon cancer DLD-1 cells differing in ploidy and chromosome stability

1 Mar 2018

Abstract excerpt

Although aneuploidy is poorly tolerated during embryogenesis, aneuploidy and whole chromosomal instability (CIN) are common hallmarks of cancer, raising the question of how cancer cells can thrive in spite of chromosome aberrations. Here we present a comprehensive and quantitative proteomics analysis of isogenic DLD-1 colorectal adenocarcinoma cells lines, aimed at identifying cellular responses to changes in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Cancer-related Molecular Pathways
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29496963
DOI: 10.1091/mbc.e17-10-0577

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative proteomic and phosphoproteomic comparison of human colon cancer DLD-1 cells differing in ploidy and chromosome stabilityPMID 29496963Read ↗

Chromosomal aneuploidy affects the global proteome equilibrium of colorectal cancer cells.Semantic proximity Read ↗

Chromosomal Aneuploidy Affects the Global Proteome Equilibrium of Colorectal Cancer CellsSemantic proximity Read ↗

Cyclin D mediates tolerance of genome-doubling in cancers with functional p53Semantic proximity Read ↗

Pan-cancer proteogenomic landscape of whole-genome doubling reveals putative therapeutic targets in various cancer typesSemantic proximity Read ↗

Extensive protein dosage compensation in aneuploid human cancersSemantic proximity Read ↗

Colorectal Cancer Cell Line Proteomes Are Representative of Primary Tumors and Predict Drug Sensitivity.Semantic proximity Read ↗

Selective advantage of trisomic human cells cultured in non-standard conditionsSemantic proximity Read ↗

Regulation of protein complex partners as a compensatory mechanism in aneuploid tumorsSemantic proximity Read ↗

Regulation of protein complex partners as a compensatory mechanism in aneuploid tumorsSemantic proximity Read ↗

Stage‐specific alterations of the genome, transcriptome, and proteome during colorectal carcinogenesisSemantic proximity Read ↗

A Transcriptional and Metabolic Signature of Primary Aneuploidy Is Present in Chromosomally Unstable Cancer Cells and Informs Clinical PrognosisSemantic proximity Read ↗

Chromosomal instability, tolerance of mitotic errors and multidrug resistance are promoted by tetraploidization in human cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.