Article
CTNNB1 mutations in basal cell adenoma of the salivary gland.
Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Oct 2018
Lee Yi-Hsuan, Huang Wen-Chih, Hsieh Min-Shu
Abstract excerpt
BACKGROUND/PURPOSE: Basal cell adenoma (BCA) and basal cell adenocarcinoma (BCAC) are uncommon salivary gland tumors comprising proliferation of basaloid cells. Nuclear β-catenin expression and mutations in its encoding gene (CTNNB1) are reported to be specific to BCA. PIK3CA mutations are only found in BCAC not in BCA. However, in previous studies the number of cases was relatively small. The present study...
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