Article
Protein O-mannosyltransferases are required for sterigmatocystin production and developmental processes in Aspergillus nidulans.
Current genetics - 1 Oct 2018
Le Thi Huynh Tram, Oki Ayana, Goto Masatoshi, Shimizu Kiminori
Abstract excerpt
Aspergillus nidulans produces sterigmatocystin (ST), a precursor of a carcinogenic secondary metabolite aflatoxin (AF), during its developmental process. ST biosynthesis has been shown to be affected by various regulatory factors. In this study, we investigated the involvement of O-mannosyltransferases (PmtA, PmtB, PmtC), in ST production and morphological development. Deletion of pmtA (ΔpmtA), pmtB (ΔpmtB) or...
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