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Article

Mutational and Functional Analysis of FANCB as a Candidate Gene for Sporadic Head and Neck Squamous Cell Carcinomas.

Anticancer research - 1 Mar 2018

Glaas Marcel F, Wiek Constanze, Wolter Linda-Maria, Roellecke Katharina, Balz Vera, Okpanyi Vera, Wagenmann Martin, Hoffmann Thomas Karl, Grässlin Rene, Plettenberg Christian, Schipper Jörg, Hanenberg Helmut, Scheckenbach Kathrin

Abstract excerpt

BACKGROUND/AIM: Head and neck squamous cell carcinomas (HNSCCs) form a heterogeneous tumor entity located throughout the oral cavity, pharynx and larynx that is caused predominantly by chemically or virally induced carcinogenesis. Heterozygous germline mutations in cancer susceptibility genes might also lead to increased incidence of HNSCCs. As DNA stability is typically impaired in HNSCC cells and genes of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fanconi Anemia Complementation Group Proteins

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Source

Identifiers

PMID: 29491055
DOI: 10.21873/anticanres.12354

Genes

FANCB

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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