Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Development of a Vaccine Against Meningococcus B Using Reverse Vaccinology

16 Apr 2019

Abstract excerpt

serogroup B (MenB) was systematically analyzed to identify proteins predicted to be secreted or exported to the outer membrane. This identified hundreds of genes coding for potential surface-exposed antigens. These were amplified, cloned in expression vectors and used to immunize mice. Antisera against 350 recombinant antigens were obtained and analyzed in a panel of immunological assays from which 28 were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Infections and Vaccines
Share to Infective Endocarditis Diagnosis and Management
Share to Pneumonia and Respiratory Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31040844
DOI: 10.3389/fimmu.2019.00751

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Development of a Vaccine Against Meningococcus B Using Reverse VaccinologyPMID 31040844Read ↗

Immunogenicity of Two Investigational Serogroup B Meningococcal Vaccines in the First Year of LifeSemantic proximity Read ↗

Meningococcal serogroup B vaccines: Estimating breadth of coverageSemantic proximity Read ↗

Novel approaches to Neisseria meningitidis vaccine designSemantic proximity Read ↗

Looking beyond meningococcal B with the 4CMenB vaccine: the Neisseria effectSemantic proximity Read ↗

Strategies for Development of Universal Vaccines Against Meningococcal Serogroup B DiseaseSemantic proximity Read ↗

OpcA and PorB are novel bactericidal antigens of the 4CMenB vaccine in mice and humansSemantic proximity Read ↗

BexseroSemantic proximity Read ↗

MATS: Global coverage estimates for 4CMenB, a novel multicomponent meningococcal B vaccineSemantic proximity Read ↗

Neisseria meningitidis factor H-binding protein fHbp: a key virulence factor and vaccine antigenSemantic proximity Read ↗

The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeaeSemantic proximity Read ↗

Bioinformatics Analysis of Global Diversity in Meningococcal Vaccine Antigens over the Past 10 Years; Vaccine Efficiency PrognosisSemantic proximity Read ↗

A combination recombinant protein and outer membrane vesicle vaccine against serogroup B meningococcal diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.