Article
A Genetic Screen Identifies PRP18a, a Putative Second Step Splicing Factor Important for Alternative Splicing and a Normal Phenotype in Arabidopsis thaliana.
G3 (Bethesda, Md.) - 28 Mar 2018
Kanno Tatsuo, Lin Wen-Dar, Chang Chia-Liang, Matzke Marjori, Matzke Antonius J M
Abstract excerpt
Splicing of pre-mRNA involves two consecutive trans-esterification steps that take place in the spliceosome, a large dynamic ribonucleoprotein complex situated in the nucleus. In addition to core spliceosomal proteins, each catalytic step requires step-specific factors. Although the Arabidopsis thaliana genome encodes around 430 predicted splicing factors, functional information about these proteins is limited....
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