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Article

Effect of placental sex hormone-binding globulin single nucleotide polymorphism rs6259 on protein and function in gestational diabetes mellitus.

International journal of molecular medicine - 1 May 2018

Zhang Xuan, Sun Lei, Jin Zhen

Abstract excerpt

Sex hormone-binding globulin (SHBG) has a key role in the occurrence and development of the gestational diab-etes mellitus (GDM). Single nucleotide polymorphism (SNP) rs6259 is a functional site in SHBG gene, which is suspected to regulate the SHBG level. The present study explored the placental SHBG SNP rs6259 distribution in Chinese pregnant women and the influence on placental SHBG concentrations, to assess...

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Identifiers

PMID: 29484425
DOI: 10.3892/ijmm.2018.3503

Genes

SHBG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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