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Article

SHBG expression is correlated with PI3K/AKT pathway activity in a cellular model of human insulin resistance

3 Jan 2018

Abstract excerpt

Decreased sex hormone-binding globulin (SHBG) expression is an independent risk factor for gestational diabetes mellitus(GDM).However, the mechanisms that link low SHBG expression and insulin resistance in GDM is unclear. In this study, we investigated the placenta SHBG in the PI3K/AKT pathway to reveal the mechanism that links decreased SHBG to insulin resistance. A insulin resistance cells model was established...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29298529
DOI: 10.1080/09513590.2017.1411474

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