Article
Age-related clonal hematopoiesis and HIV infection are associated with geriatric outcomes: The ARCHIVE study.
Cell reports. Medicine - 17 Dec 2024
Han Win Min, Sazzad Hossain M S, Bloch Mark, Baker David A, Roth Norman, Bowden-Reid Ellen, Smith Don E, Hoy Jennifer F, Woolley Ian, Finlayson Robert, Templeton David J, Matthews Gail V, Costello Jane, Dawson Mark A, Dawson Sarah-Jane, Polizzotto Mark N, Petoumenos Kathy, Yeh Paul, Dharan Nila J
Abstract excerpt
While HIV infection and clonal hematopoiesis (CH) have been linked with inflammatory dysregulation and an increased risk of aging-related comorbidities, their relationship with clinical geriatric syndromes has not been well defined. In the Age-related Clonal Haematopoiesis in an HIV Evaluation Cohort (ARCHIVE) study (NCT04641013), we measure associations between HIV and CH and geriatric syndromes. Of 345...
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