Article
Gene-diet interaction effects on BMI levels in the Singapore Chinese population.
Nutrition journal - 24 Feb 2018
Chang Xuling, Dorajoo Rajkumar, Sun Ye, Han Yi, Wang Ling, Khor Chiea-Chuen, Sim Xueling, Tai E-Shyong, Liu Jianjun, Yuan Jian-Min, Koh Woon-Puay, van Dam Rob M, Friedlander Yechiel, Heng Chew-Kiat
Abstract excerpt
BACKGROUND: Recent genome-wide association studies (GWAS) have identified 97 body-mass index (BMI) associated loci. We aimed to evaluate if dietary intake modifies BMI associations at these loci in the Singapore Chinese population. METHODS: We utilized GWAS information from six data subsets from two adult Chinese population (N = 7817). Seventy-eight genotyped or imputed index BMI single nucleotide polymorphisms...
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