Article
Association of the A/G polymorphism at position 49 in exon 1 of CTLA-4 with the susceptibility to unexplained recurrent spontaneous abortion in the Chinese population.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Feb 2005
Wang Xipeng, Lin Qide, Ma Zhengwen, Hong Yan, Zhao Aimin, Di Wen, Lu Peihua
Abstract excerpt
PROBLEM: To investigate whether the A/G polymorphism at position 49 in exon 1 of cytotoxic T lymphocyte antigen-4 (CTLA-4) gene, which delivers a negative signal to T-cell activation, confers the susceptibility to unexplained recurrent spontaneous abortion in the Chinese population. METHOD OF STUDY: A total of 168 patients with unexplained recurrent spontaneous abortion (RSA), who were treated in the Renji...
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