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EGR3 Immediate Early Gene and the Brain-Derived Neurotrophic Factor in Bipolar Disorder

5 Feb 2018

Abstract excerpt

Bipolar disorder (BD) is a severe mental illness with a strong genetic component, involving complex interactions between numerous genes and environmental factors. Immediate early genes (IEGs) are activated in the brain in response to environmental stimuli, such as stress. The potential to translate environmental stimuli into long-term changes in brain has led to increased interest in a potential role for these...

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PMID: 29459824
DOI: 10.3389/fnbeh.2018.00015

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