Article
Genetic association of the EGR2 gene with bipolar disorder in Korea.
Experimental & molecular medicine - 29 Feb 2012
Kim Se Hyun, Song Joo Youn, Joo Eun Jeong, Lee Kyu Young, Shin Soon Young, Lee Young Han, Ahn Yong Min, Kim Yong Sik
Abstract excerpt
The early growth response gene 2 (EGR2) is located at chromosome 10q21, one of the susceptibility loci in bipolar disorder (BD). EGR2 is involved in cognitive function, myelination, and signal transduction related to neuregulin-ErbB receptor, Bcl-2 family proteins, and brain-derived neurotrophic factor. This study investigated the genetic association of the EGR2 gene with BD and schizophrenia (SPR) in Korea. In...
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