Article
Quantitative profiling reveals minor changes of T cell receptor repertoire in response to subunit inactivated influenza vaccine.
Vaccine - 14 Mar 2018
Sycheva Anastasiia L, Pogorelyy Mikhail V, Komech Ekaterina A, Minervina Anastasia A, Zvyagin Ivan V, Staroverov Dmitriy B, Chudakov Dmitriy M, Lebedev Yuri B, Mamedov Ilgar Z
Abstract excerpt
Vaccination against influenza is widely used to protect against seasonal flu epidemic although its effectiveness is debated. Here we performed deep quantitative T cell receptor repertoire profiling in peripheral blood of a healthy volunteer in response to trivalent subunit influenza vaccine. We did not observe significant rebuilding of peripheral blood T cell receptors composition in response to vaccination....
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