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Article

Select and resequence reveals relative fitness of bacteria in symbiotic and free-living environments.

Proceedings of the National Academy of Sciences of the United States of America - 6 Mar 2018

Burghardt Liana T, Epstein Brendan, Guhlin Joseph, Nelson Matt S, Taylor Margaret R, Young Nevin D, Sadowsky Michael J, Tiffin Peter

Abstract excerpt

Assays to accurately estimate relative fitness of bacteria growing in multistrain communities can advance our understanding of how selection shapes diversity within a lineage. Here, we present a variant of the "evolve and resequence" approach both to estimate relative fitness and to identify genetic variants responsible for fitness variation of symbiotic bacteria in free-living and host environments. We...

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Identifiers

PMID: 29453274
DOI: 10.1073/pnas.1714246115
PMCID: PMC5877963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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