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Article

Alloimmune neonatal neutropenia linked to anti-HNA-4a.

Transfusion medicine (Oxford, England) - 1 Feb 2003

Fung Y L, Pitcher L A, Willett J E, Reed C, Mison L, Bux J, Eiber G, Minchinton R M

Abstract excerpt

This is a novel case report of alloimmune neonatal neutropenia (ANN) linked to the neutrophil antibody anti-HNA-4a (MART). Since its discovery, the HNA-4a antigen has never been associated with any clinical neutropenia. A first-born neonate with respiratory distress was found to be severely neutropenic, because of ANN. The broad reactivity of the antibody together with its capture by CD11b and CD18 in monoclonal...

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Identifiers

PMID: 12581454
DOI: 10.1046/j.1365-3148.2003.00413.x

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