Article
Robust Phenotypic Activation of Eosinophils during Experimental Toxocara canis Infection.
Frontiers in immunology - 1 Jan 2018
Rodolpho Joice Margareth de Almeida, Camillo Luciana, Araújo Márcio Sobreira Silva, Speziali Elaine, Coelho-Dos-Reis Jordana Grazziela, Correia Ricardo de Oliveira, Neris Débora Meira, Martins-Filho Olindo Assis, Teixeira-Carvalho Andréa, Anibal Fernanda de Freitas
Abstract excerpt
Eosinophils are multifunctional cells that have cytotoxic proinflammatory activities and stimulate CD4+ T-cells in experimental models of allergy and parasitic infections. Eosinophils, when exposed to antigens, are activated, expressing the CD38/CD69 molecules and exhibited increased expression of major histocompatibility complex (MHC-II), CD80 and CD86, suggesting they play a role upon Toxocara canis antigen...
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