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Myeloid Cell Phenotypes in Susceptibility and Resistance to Helminth Parasite Infections.

Microbiology spectrum - 1 Dec 2016

Maizels Rick M, Hewitson James P

Abstract excerpt

Many major tropical diseases are caused by long-lived helminth parasites that are able to survive by modulation of the host immune system, including the innate compartment of myeloid cells. In particular, dendritic cells and macrophages show markedly altered phenotypes during parasite infections. In addition, many specialized subsets such as eosinophils and basophils expand dramatically in response to these...

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PMID: 28087937
DOI: 10.1128/microbiolspec.MCHD-0043-2016

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