Article
Resident intestinal eosinophils constitutively express antigen presentation markers and include two phenotypically distinct subsets of eosinophils.
Immunology - 1 Jun 2018
Xenakis Jason J, Howard Emily D, Smith Kalmia M, Olbrich Courtney L, Huang Yanjun, Anketell Dilanjan, Maldonado Samuel, Cornwell Evangeline W, Spencer Lisa A
Abstract excerpt
Intestinal eosinophils are implicated in homeostatic and disease-associated processes, yet the phenotype of intestinal tissue-dwelling eosinophils is poorly defined and their roles in intestinal health or disease remain enigmatic. Here we probed the phenotype and localization of eosinophils constitutively homed to the small intestine of naive mice at baseline, and of antigen-sensitized mice following intestinal...
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