Article
Re-evaluating Strategies to Define the Immunoregulatory Roles of miRNAs.
Trends in immunology - 1 Aug 2017
Forero Adriana, So Lomon, Savan Ram
Abstract excerpt
miRNAs play an important role in fine-tuning host immune homeostasis and responses through the regulation of mRNA stability and translation. Studies have demonstrated that miRNA-mediated regulation of gene expression has a profound impact on immune cell development, function, and response to invading pathogens. As we continue to examine the mechanisms by which miRNAs maintain the balance between robust protective...
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