Association between TNF-α polymorphisms and gestational diabetes mellitus: a meta-analysis and trial sequential analysis.

Abstract excerpt

AIM: Previous studies have yielded controversial results about the link between tumor necrosis factor-α (TNF-α) gene polymorphisms (rs1800629, rs361525, and rs1799724) and risk of gestational diabetes mellitus (GDM). Thus, a meta-analysis was performed to obtain a more conclusive result. MATERIALS AND METHODS: Eligible studies were retrieved in PubMed, Embase, China National Knowledge Infrastructure, and Wanfang...