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Article

SNX18 regulates ATG9A trafficking from recycling endosomes by recruiting Dynamin‐2

7 Feb 2018

Abstract excerpt

Trafficking of mammalian ATG9A between the Golgi apparatus, endosomes and peripheral ATG9A compartments is important for autophagosome biogenesis. Here, we show that the membrane remodelling protein SNX18, previously identified as a positive regulator of autophagy, regulates ATG9A trafficking from recycling endosomes. ATG9A is recruited to SNX18-induced tubules generated from recycling endosomes and accumulates...

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PMID: 29437695
DOI: 10.15252/embr.201744837

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