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Article

Atg8‐family interacting motif crucial for selective autophagy

17 Jan 2010

Abstract excerpt

Autophagy is a bulk degradation system conserved among most eukaryotes. Recently, autophagy has been shown to mediate selective degradation of various targets such as aggregated proteins and damaged or superfluous organelles. Structural studies have uncovered the conserved specific interactions between autophagic receptors and Atg8-family proteins through WXXL-like sequences, which we term the Atg8-family...

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PMID: 20083108
DOI: 10.1016/j.febslet.2010.01.018

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