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Article

Drosophila Golgi membrane protein Ema promotes autophagosomal growth and function.

Proceedings of the National Academy of Sciences of the United States of America - 1 May 2012

Kim Sungsu, Naylor Sarah A, DiAntonio Aaron

Abstract excerpt

Autophagy is a self-degradative process in which cellular material is enclosed within autophagosomes and trafficked to lysosomes for degradation. Autophagosomal biogenesis is well described; however mechanisms controlling the growth and ultimate size of autophagosomes are unclear. Here we demonstrate that the Drosophila membrane protein Ema is required for the growth of autophagosomes. In an ema mutant,...

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Identifiers

PMID: 22493244
DOI: 10.1073/pnas.1120320109
PMCID: PMC3344964

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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