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Article

Compounds with Potential Activity against Mycobacterium tuberculosis.

Antimicrobial agents and chemotherapy - 1 Apr 2018

Sao Emani C, Williams M J, Wiid I J, Baker B, Carolis C

Abstract excerpt

The high acquisition rate of drug resistance by Mycobacterium tuberculosis necessitates the ongoing search for new drugs to be incorporated in the tuberculosis (TB) regimen. Compounds used for the treatment of other diseases have the potential to be repurposed for the treatment of TB. In this study, a high-throughput screening of compounds against thiol-deficient Mycobacterium smegmatis strains and subsequent...

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PMID: 29437626
DOI: 10.1128/AAC.02236-17
PMCID: PMC5913991

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