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1,4-Azaindole, a Potential Drug Candidate for Treatment of Tuberculosis

24 Jun 2014

Abstract excerpt

New therapeutic strategies against multidrug-resistant (MDR) and extensively drug-resistant (XDR) Mycobacterium tuberculosis are urgently required to combat the global tuberculosis (TB) threat. Toward this end, we previously reported the identification of 1,4-azaindoles, a promising class of compounds with potent antitubercular activity through noncovalent inhibition of decaprenylphosphoryl-β-D-ribose...

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PMID: 24957839
DOI: 10.1128/aac.03233-14

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