Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia

10 Oct 2017

Abstract excerpt

Schizophrenia is a neurodevelopmental disorder that affects up to 1% of the general population. Various genes show associations with schizophrenia and a very weak nominal association with the tight junction protein, claudin-5, has previously been identified. Claudin-5 is expressed in endothelial cells forming part of the blood-brain barrier (BBB). Furthermore, schizophrenia occurs in 30% of individuals with 22q11...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced Neuroimaging Techniques and Applications
Share to Barrier Structure and Function Studies
Share to Neurological Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28993710
DOI: 10.1038/mp.2017.156

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Dose-dependent expression of claudin-5 is a modifying factor in schizophreniaPMID 28993710Read ↗

Blood-brain barrier associated tight junction disruption is a hallmark feature of major psychiatric disordersSemantic proximity Read ↗

A transgenic zebrafish model for the in vivo study of the blood and choroid plexus brain barriers using claudin 5Semantic proximity Read ↗

A transgenic zebrafish model for the <i>in vivo</i> study of the blood and choroid plexus brain barriers using claudin 5Semantic proximity Read ↗

Pumilio-1 mediated translational control of claudin-5 at the blood-brain barrier.Semantic proximity Read ↗

The region‐selective regulation of endothelial claudin‐5 expression and signaling in brain health and disordersSemantic proximity Read ↗

Claudin 5 expression in mouse seminiferous epithelium is dependent upon the transcription factor ets variant 5 and contributes to blood-testis barrier function.Semantic proximity Read ↗

Selective decrease in paracellular conductance of tight junctions: role of the first extracellular domain of claudin-5.Semantic proximity Read ↗

Down Regulated Expression of Claudin-1 and Claudin-5 and Up Regulation of β-Catenin: Association with Human Glioma ProgressionSemantic proximity Read ↗

A claudin5-binding peptide enhances the permeability of the blood-brain-barrierSemantic proximity Read ↗

Mechanisms of transcriptional activation of the mouse claudin-5 promoter by estrogen receptor alpha and beta.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.