Article
Characterization of the role of global regulator FliA in the pathophysiology of Pseudomonas aeruginosa infection.
Research in microbiology - 1 Apr 2018
Lo Yi-Ling, Chen Chyi-Liang, Shen Lunda, Chen Ying-Ching, Wang Yi-Hsin, Lee Chung-Chan, Wang Lian-Chen, Chuang Chih-Hsien, Janapatla Rajendra Prasad, Chiu Cheng-Hsun, Chang Hwan-You
Abstract excerpt
FliA is known to be a sigma factor that regulates bacterial flagella gene expression. Accumulating evidence suggests that FliA is involved in bacterial behavior other than motility. To elucidate the contribution of FliA to Pseudomonas aeruginosa pathophysiology, we analyzed the biological properties and gene expression profiles of a ΔfliA mutant. Transcriptome analysis results demonstrated that the expression...
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