Article
Regulation of Motility and Phenazine Pigment Production by FliA Is Cyclic-di-GMP Dependent in Pseudomonas aeruginosa PAO1.
PloS one - 1 Jan 2016
Lo Yi-Ling, Shen Lunda, Chang Chih-Hsuan, Bhuwan Manish, Chiu Cheng-Hsun, Chang Hwan-You
Abstract excerpt
The transcription factor FliA, also called sigma 28, is a major regulator of bacterial flagellar biosynthesis genes. Growing evidence suggest that in addition to motility, FliA is involved in controlling numerous bacterial behaviors, even though the underlying regulatory mechanism remains unclear. By using a transcriptional fusion to gfp that responds to cyclic (c)-di-GMP, this study revealed a higher c-di-GMP...
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