Article
Genetic variants in sex hormone pathways and the risk of type 2 diabetes among African American, Hispanic American, and European American postmenopausal women in the US.
Journal of diabetes - 1 Jun 2018
Goto Atsushi, Chen Brian H, Chan Kei-Hang K, Lee Cathy, Nelson Sarah C, Crenshaw Andrew, Bookman Ebony, Margolis Karen L, Sale Michèle M, Ng Maggie C Y, Reiner Alexander P, Liu Simin
Abstract excerpt
BACKGROUND: Sex hormones are implicated in the development of diabetes. However, whether genetic variations in sex hormone pathways (SHPs) contribute to the risk of type 2 diabetes mellitus (T2DM) remains to be determined. This study investigated associations between genetic variations in all candidate genes in SHPs and T2DM risk among a cohort of women participating in the Women's Health Initiative (WHI)....
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