Article
[Specificity of binding of regulatory proteins with DNA: possible explanation in terms of "point" interactions].
Molekuliarnaia biologiia - 1 Jan 2000
Gul'tiaev A P, Zheltovskiĭ N V
Abstract excerpt
On the basis of the previously obtained data on the specificity of the interactions between amino acids and nucleotide bases an attempt is undertaken to explain the origin of the specificity of binding of repressors and cro proteins to corresponding operator DNA sequences in phages lambda and P22. The rules describing the interactions between amino acids and bases are supposed to be the same for the binding of...
Topics
- Amino Acid Sequence
- Bacteriophage lambda
- Base Sequence
- DNA, Viral
- DNA-Binding Proteins
- Models, Genetic
- Mutation
- Operon
- Repressor Proteins
- Transcription Factors
- Viral Proteins
