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Article

Changes in DNA Methylation from Age 18 to Pregnancy in Type 1, 2, and 17 T Helper and Regulatory T-Cells Pathway Genes.

International journal of molecular sciences - 6 Feb 2018

Iqbal Sabrina, Lockett Gabrielle A, Holloway John W, Arshad S Hasan, Zhang Hongmei, Kaushal Akhilesh, Tetali Sabarinath R, Mukherjee Nandini, Karmaus Wilfried J J

Abstract excerpt

To succeed, pregnancies need to initiate immune biases towards T helper 2 (Th2) responses, yet little is known about what establishes this bias. Using the Illumina 450 K platform, we explored changes in DNA methylation (DNAm) of Th1, Th2, Th17, and regulatory T cell pathway genes before and during pregnancy. Female participants were recruited at birth (1989), and followed through age 18 years and their pregnancy...

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Identifiers

PMID: 29415463
DOI: 10.3390/ijms19020477
PMCID: PMC5855699

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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