Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of the human TIMM23 and TIMM23B genes is regulated by the GABP transcription factor.

Biochimica et biophysica acta. Gene regulatory mechanisms - 1 Feb 2018

Prieto-Ruiz Jesús A, Alis Rafael, García-Benlloch Sandra, Sáez-Atiénzar Sara, Ventura Ignacio, Hernández-Andreu José M, Hernández-Yago José, Blesa José R

Abstract excerpt

The TIM23 protein is a key component of the mitochondrial import machinery in yeast and mammals. TIM23 is the channel-forming subunit of the translocase of the inner mitochondrial membrane (TIM23) complex, which mediates preprotein translocation across the mitochondrial inner membrane. In this paper, we aimed to characterize the promoter region of the highly similar human TIM23 orthologs: TIMM23 and TIMM23B....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Tumor
Share to HEK293 Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin J Recombination Signal Sequence-Binding Protein

Share to Mitochondrial Membrane Transport Proteins

Share to Mitochondrial Precursor Protein Import Complex Proteins

Share to Protein Isoforms

Share to RNA Interference

Share to Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 29413900
DOI: 10.1016/j.bbagrm.2018.01.006

Genes

TIMM23
RBPJ
GABPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of the human TIMM23 and TIMM23B genes is regulated by the GABP transcription factor.PMID 29413900Read ↗

Hotspots for Disease-Causing Mutations in the Mitochondrial TIM23 Import Complex.Semantic proximity Read ↗

Role of Tim17 Transmembrane Regions in Regulating the Architecture of Presequence Translocase and Mitochondrial DNA Stability.Semantic proximity Read ↗

METTL23, a transcriptional partner of GABPA, is essential for human cognition.Semantic proximity Read ↗

Role of Magmas in protein transport and human mitochondria biogenesis.Semantic proximity Read ↗

OCIAD1 and prohibitins regulate the stability of the TIM23 protein translocaseSemantic proximity Read ↗

Multiple variants of the human presequence translocase motor subunit Magmas govern the mitochondrial import.Semantic proximity Read ↗

The role of the TIM8-13 complex in the import of Tim23 into mitochondria.Semantic proximity Read ↗

InVivo Dissection of the Intrinsically Disordered Receptor Domain of Tim23.Semantic proximity Read ↗

Functional crosstalk between the carrier translocase machinery and YME1 complex maintains mitochondrial proteostasis and integritySemantic proximity Read ↗

Neurological phenotype and reduced lifespan in heterozygous Tim23 knockout mice, the first mouse model of defective mitochondrial import.Semantic proximity Read ↗

The channel-forming Sym1 protein is transported by the TIM23 complex in a presequence-independent manner.Semantic proximity Read ↗

Mitochondrial protein import motor: differential role of Tim44 in the recruitment of Pam17 and J-complex to the presequence translocase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.