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Identification of reliable biomarkers of human papillomavirus 16 methylation in cervical lesions based on integration status using high-resolution melting analysis

23 Jan 2018

Abstract excerpt

Background: The dynamic methylation of human papillomavirus (HPV) 16 DNA is thought to be associated with the progression of cervical lesions. Previous studies that did not consider the physical status of HPV 16 may have incorrectly mapped HPV 16 methylomes. In order to identify reliable biomarkers for squamous cervical cancer (SCC), we comprehensively evaluated the methylation of HPV 16 depending on the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29410710
DOI: 10.1186/s13148-018-0445-8

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