Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bioactive Dietary VDR Ligands Regulate Genes Encoding Biomarkers of Skin Repair That Are Associated with Risk for Psoriasis.

Nutrients - 4 Feb 2018

Karrys Amitis, Rady Islam, Chamcheu Roxane-Cherille N, Sabir Marya S, Mallick Sanchita, Chamcheu Jean Christopher, Jurutka Peter W, Haussler Mark R, Whitfield G Kerr

Abstract excerpt

Treatment with 1,25-dihydroxyvitamin D₃ (1,25D) improves psoriasis symptoms, possibly by inducing the expression of late cornified envelope (LCE)3 genes involved in skin repair. In psoriasis patients, the majority of whom harbor genomic deletion of LCE3B and LCE3C (LCE3C_LCE3B-del), we propose that certain dietary analogues of 1,25D activate the expression of residual LCE3A/LCE3D/LCE3E genes to compensate for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Curcumin
Share to Diet

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Docosahexaenoic Acids

Share to Keratinocytes

Share to Ligands

Share to Psoriasis

Share to Receptors, Calcitriol

Source

Open in PubMed Open full text

Identifiers

PMID: 29401702
DOI: 10.3390/nu10020174
PMCID: PMC5852750

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bioactive Dietary VDR Ligands Regulate Genes Encoding Biomarkers of Skin Repair That Are Associated with Risk for Psoriasis.PMID 29401702Read ↗

Transcriptomic Profiling of Lesional and Perilesional Skin in Atopic Dermatitis Suggests Barrier Dysfunction, Inflammatory Activation, and Alterations to Vitamin D MetabolismSemantic proximity Read ↗

Transcriptomic Profiling of Lesional and Perilesional Skin in Atopic Dermatitis Suggests Barrier Dysfunction, Inflammatory Activation, and Alterations to Vitamin D MetabolismSemantic proximity Read ↗

Psoriasis-Associated Late Cornified Envelope (LCE) Proteins Have Antibacterial Activity.Semantic proximity Read ↗

Potential Role of the Epidermal Differentiation Complex in the Pathogenesis of PsoriasisSemantic proximity Read ↗

Non-Skeletal Roles of Vitamin D: Epithelial Barrier Function and Immune Regulation in Chronic DiseaseSemantic proximity Read ↗

Transcriptional Profiling after Lipid Raft Disruption in Keratinocytes Identifies Critical Mediators of Atopic Dermatitis PathwaysSemantic proximity Read ↗

Retinoid‐responsive transcriptional changes in epidermal keratinocytesSemantic proximity Read ↗

Psoriasis Risk Genes of the Late Cornified Envelope-3 Group Are Distinctly Expressed Compared with Genes of Other LCE GroupsSemantic proximity Read ↗

Gelsolin Counteracts ER Stress-Driven Inflammatory Circuits in Psoriasis-like DermatitisSemantic proximity Read ↗

NF-κB-c-Rel in psoriasis: genetic susceptibility, immunopathogenic circuits, and emerging therapeutic opportunities.Semantic proximity Read ↗

Gene expression profiling reveals new protective roles for vitamin C in human skin cellsSemantic proximity Read ↗

Vitamin D: A master example of nutrigenomicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.